The Centre of Excellence for Pharmaceutical Sciences (CoEPS) is the fruit of a new vision towards the future. Academic excellence has moved beyond lecture halls and auditoriums into the realm of industry. The School of Pharmacy has stepped out of its shell to harness this change and ride the wave of integration between the academia and the industry.
As the Director of the CoEPS, I would love to see the change taking shape right here, right now. It is a very timely transition as the work market demands characters of high quality and expertise. This is only possible if the academia and industry work hand-in-hand towards producing these competent individuals.
The advent and advancement of technology has placed the world within our palms in the form of small screens. Globalisation is also inevitable. Hence, academia has to change too. Ideas of having university in-situ within an industry is also an approachable trend of the future. Our students will be given that opportunity to equip themselves for better competitiveness.
KPJ Healthcare UC, School of Pharmacy shall not wait any longer. The CoEPS provides the opportunity for our students and staff to soar to higher standards by opening our doors to the industry and venturing into their worlds as well. May this integration carry us to higher achievements.
Mdm Bama V.V. Menon
Director CoEPS and Deputy Dean,
School of Pharmacy,
B.Pharm (Hons), M. Clin Pharm
RPh, MPS, GCP Certified
Pre Formulation & Dosage Form Design
We offer the basic pre-formulation studies for drugs and excipients from natural and synthetic origin. Bulk characterization, solubility analysis, enhancement of solubility of poorly soluble drugs, and the drug excipient compatibility studies are the major areas covered as part of the pre-formulation research and training.
We explore the natural polymers and excipients extracted from herbal and marine sources to develop dosage forms like TABLETS, SUSPENSIONS, EMULSIONS, GELS, CREAMS, etc. for medicinal and cosmetic purposes.
Our laboratory is well equipped with research scale sophisticated equipment like the mixer, high shear granulator, fluidized bed dryer, automated double-layer tablet press, pan coating machine, etc. for research and training on solid oral dosage forms such as conventional and sustained-release tablets. Our focus of research and training is the development of tablets and multi-particulate drug delivery systems including granules, beads, and microspheres using tablet press, granulators and extruders, emulsification, and solvent evaporation techniques. Quality analysis through mock IPQC tests (Hardness, friability, content uniformity, disintegration, dissolution, compatibility studies – IR, HPLC.) are run to determine the safety, efficacy, and stability of the prepared dosage forms.
- Novel Transdermal & Trans mucosal Drug Delivery Systems
Gels are the most accepted semi-solid dosage forms due to their elegant appearance, ease of application, and removal. Gels are used as muco-adhesive formulations for increased contact time and better efficacy. At our laboratory, projects are undertaken to develop novel bio-adhesive and muco-adhesive gels using natural and synthetic polymers, and in-situ gelling technology for topical and systemic administration of therapeutic agents.
- Instruments/Facilities Available:
- Bulk Density Apparatus
- Angle of Repost Apparatus
- Sieve Shaker
- 3D Mixer
- High Shear Granulator
- Fluidised Bed Dryer
- Tablet Press
- Coating Machine
- Dissolution Apparatus
- Diffusion Cell
- Fourier Transform Infra –Red Spectrophotometer
- Flame Photometer
- High Performance Liquid Chromatography
- Gas Chromatography
- Rotary Vacuum Evaporator
- Drug Discovery & Screening
The facilities available for toxicological studies (Acute toxicity, 14 day and 28 day Repeated dose toxicity, screening of drugs by POWER LAB System (AD instrument). The facilities include for screening of drugs to treat pathologies of cardiovascular system (hypertension, dyslipidemia, atherosclerosis and stroke Models. Central Nervous System screening facilities for Anxiety, depression and memory related problems. Other related facilities also available for metabolic disorders and inflammation. Development of suitable animal models, to evaluate synthetic compounds, plant extracts or fractions are the activities of the project in quest of new target based drugs. We undertake academic and industrial research projects and provide training for toxicological studies and pharmacological studies for drug development.
- Experiments on Pre-Clinical Animal Model
Screening methods in research models i.e. CNS evaluation- ICV injection, cerebral lesion methods, neurotransmitter evaluation methods, Anti-diabetic, Anti-asthmatic, Antiepileptic, Antiulcer, Aphrodisiac, CVS (POWER LAB) and analgesic and anti-inflammatory evaluation.
- Instruments/Facilities Available:
- PowerLab – Cardiovascular/ Respiratory Apparatus
- Auto analyzer
- ELISA plate Reader
- Rota Rod Apparatus
- Hot Plate Instrument
- Tail Flick Apparatus
- Open Field apparatus
- Y Maze
- Digital Microscope